Annotation Detail

Information
Associated Genes
INS
Associated Variants
INS MUTATION
INS MUTATION
Associated Disease
Premature aging syndrome
Source Database
DisGeNET
Description
Finally, the accelerated cellular senescence was also observed at the organismal level as shown by down-regulation of insulin-like growth factor 1 (IGF-1), a hallmark of premature ageing.
Pubmed
25274775
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs