Annotation Detail
Information
- Associated Genes
- LRP8
- Associated Variants
-
NC_000019.10:g.44911194T>C
LRP8 p.Asp874= (p.D874=) ( ENST00000354412.7, ENST00000668448.1, ENST00000667377.1, ENST00000306052.12, ENST00000662198.1, ENST00000347547.7, ENST00000371454.6, ENST00000662604.1, ENST00000658277.1, ENST00000657895.1 )
LRP8 p.Asp874Glu (p.D874E) ( ENST00000306052.12, ENST00000347547.7, ENST00000662198.1, ENST00000667377.1, ENST00000668448.1, ENST00000354412.7, ENST00000657895.1, ENST00000662604.1, ENST00000658277.1, ENST00000371454.6 )
LRP8 p.Gly419= (p.G419=) ( ENST00000659993.1, ENST00000371454.6, ENST00000658277.1, ENST00000662604.1, ENST00000657895.1, ENST00000668448.1, ENST00000354412.7, ENST00000667377.1, ENST00000347547.7, ENST00000662198.1, ENST00000306052.12 )
NC_000019.10:g.44911194T>C
LRP8 p.Asp874= (p.D874=) ( ENST00000306052.12, ENST00000347547.7, ENST00000354412.7, ENST00000371454.6, ENST00000657895.1, ENST00000658277.1, ENST00000662198.1, ENST00000662604.1, ENST00000667377.1, ENST00000668448.1 )
LRP8 p.Asp874Glu (p.D874E) ( ENST00000306052.12, ENST00000347547.7, ENST00000354412.7, ENST00000371454.6, ENST00000657895.1, ENST00000658277.1, ENST00000662198.1, ENST00000662604.1, ENST00000667377.1, ENST00000668448.1 )
LRP8 p.Gly419= (p.G419=) ( ENST00000306052.12, ENST00000347547.7, ENST00000354412.7, ENST00000371454.6, ENST00000657895.1, ENST00000658277.1, ENST00000659993.1, ENST00000662198.1, ENST00000662604.1, ENST00000667377.1, ENST00000668448.1 ) - Associated Disease
- schizophrenia
- Source Database
- DisGeNET
- Description
- HIMS replication analysis supported rs439401 (APOE regulatory region), and rs2297660 and rs3737983 (APOER2), with an effect on memory performance in normal aging subjects consistent with the findings in schizophrenia cases.
- Pubmed
- 22419519
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00290991572276264
- Year of publication
- 2012
Drugs