Annotation Detail
Information
- Associated Genes
- RTEL1
- Associated Variants
-
RTEL1 c.102+151A>G, RTEL1-TNFRSF6B c.102+151A>G
(
ENST00000318100.9,
ENST00000360203.11,
ENST00000370018.7,
ENST00000508582.7,
ENST00000492259.6 )
RTEL1 c.1037+140A>G, RTEL1-TNFRSF6B c.1121+140A>G ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1191+227T>C, RTEL1-TNFRSF6B c.1275+227T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1349-771T>C, RTEL1-TNFRSF6B c.1433-771T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.102+151A>G, RTEL1-TNFRSF6B c.102+151A>G ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1037+140A>G, RTEL1-TNFRSF6B c.1121+140A>G ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1191+227T>C, RTEL1-TNFRSF6B c.1275+227T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 )
RTEL1 c.1349-771T>C, RTEL1-TNFRSF6B c.1433-771T>C ( ENST00000318100.9, ENST00000360203.11, ENST00000370018.7, ENST00000508582.7, ENST00000492259.6 ) - Associated Disease
- Astrocytoma
- Source Database
- DisGeNET
- Description
- Moreover, the stratified analyses showed a decreased risk of astrocytoma associated with RTEL1 rs6089953, rs6010620 and rs2297440 (p trend = 0.022, p trend = 0.042, p trend = 0.029, respectively) as well as an increased risk of this subtype associated with RTEL1 rs4809324 (p trend = 0.033).
- Pubmed
- 26014354
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2015
Drugs