Annotation Detail
Information
- Associated Genes
- TRIB3
- Associated Variants
-
TRIB3 p.Gln111Arg (p.Q111R)
(
ENST00000217233.9,
ENST00000422053.3,
ENST00000449710.6,
ENST00000615226.5,
ENST00000714424.1,
ENST00000714425.1,
ENST00000714426.1,
ENST00000714427.1,
ENST00000714428.1 )
TRIB3 p.Gln111Arg (p.Q111R) ( ENST00000217233.9, ENST00000422053.3, ENST00000449710.6, ENST00000615226.5, ENST00000714424.1, ENST00000714425.1, ENST00000714426.1, ENST00000714427.1, ENST00000714428.1 ) - Associated Disease
- Impaired glucose tolerance
- Source Database
- DisGeNET
- Description
- In sample 1 (n=791), the association between TRIB3 Q84R and impaired glucose regulation (IGR; defined as impaired fasting glucose and/or impaired glucose tolerance and/or type 2 diabetes by OGTT) and insulin sensitivity (ISI), and its interplay with early-phase insulin secretion (i.e.
- Pubmed
- 20393693
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2010
Drugs