Annotation Detail
Information
- Associated Genes
- TERT
- Associated Variants
-
GRK3 c.114-16352C>T
(
ENST00000324198.11 )
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
PSCA c.-26C>T ( ENST00000301258.5, ENST00000513264.1 )
GRK3 c.114-16352C>T ( ENST00000324198.11 )
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 )
TERT c.1574-3777G>T ( ENST00000310581.10, ENST00000334602.10 )
PSCA c.-26C>T ( ENST00000301258.5, ENST00000513264.1 ) - Associated Disease
- Malignant neoplasm of urinary bladder
- Source Database
- DisGeNET
- Description
- In the meta-analysis, the reported risk allele for four SNPs were significantly associated with increased bladder cancer risk, including rs798766 on TACC3 at 4p16, rs9624880 on MYC at 8q24, rs2294008 on PSCA at 8q24, and rs2736100 on TERT at 5p15.
- Pubmed
- 22711262
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0115201107592116
- Year of publication
- 2012
Drugs