Annotation Detail

Information
Associated Genes
MIR149
Associated Variants
DICER1 c.*3473T>C ( ENST00000531162.7, ENST00000526495.6, ENST00000529720.2, ENST00000674628.2, ENST00000343455.8 )
MYH7B c.1977+138A>G ( ENST00000262873.13 )
GPC1 c.167-2944T>C ( ENST00000264039.7, ENST00000420138.5 )
C5orf22 c.81+58G>C ( ENST00000325366.14 )
DICER1 c.*3473T>C ( ENST00000343455.8, ENST00000526495.6, ENST00000529720.2, ENST00000531162.7, ENST00000674628.2 )
MYH7B c.1977+138A>G ( ENST00000262873.13 )
GPC1 c.167-2944T>C ( ENST00000264039.7, ENST00000420138.5 )
C5orf22 c.81+58G>C ( ENST00000325366.14 )
Associated Disease
T-Cell Lymphoma
Source Database
DisGeNET
Description
Among the 13 SNPs, four (DROSHA rs6877842, DICER rs3742330, mir149 rs2292832, and mir499 rs3746444) were significantly associated with TCL survival after adjusting for subtype and International Prognostic Index score.
Pubmed
24563077
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs