Annotation Detail
Information
- Associated Genes
- AANAT
- Associated Variants
-
BMAL1 c.1323-309C>T
(
ENST00000403482.7,
ENST00000673817.1,
ENST00000401424.6,
ENST00000389707.8,
ENST00000403290.6,
ENST00000403510.8 )
BMAL1 c.1629+242G>A ( ENST00000673817.1, ENST00000403290.6, ENST00000401424.6, ENST00000389707.8, ENST00000403510.8, ENST00000403482.7 )
BMAL1 c.1733-372T>A ( ENST00000403510.8, ENST00000673817.1, ENST00000389707.8, ENST00000401424.6, ENST00000403290.6, ENST00000403482.7 )
AANAT c.60+795G>T ( ENST00000250615.7 )
AANAT c.60+1074C>G ( ENST00000250615.7 )
RORB c.127-165C>T ( ENST00000376896.8, ENST00000396204.2 )
BMAL1 c.1323-309C>T ( ENST00000389707.8, ENST00000401424.6, ENST00000403290.6, ENST00000403482.7, ENST00000403510.8, ENST00000673817.1 )
BMAL1 c.1629+242G>A ( ENST00000389707.8, ENST00000401424.6, ENST00000403290.6, ENST00000403482.7, ENST00000403510.8, ENST00000673817.1 )
BMAL1 c.1733-372T>A ( ENST00000389707.8, ENST00000401424.6, ENST00000403290.6, ENST00000403482.7, ENST00000403510.8, ENST00000673817.1 )
AANAT c.60+795G>T ( ENST00000250615.7 )
AANAT c.60+1074C>G ( ENST00000250615.7 )
RORB c.127-165C>T ( ENST00000376896.8, ENST00000396204.2 ) - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- After applying FPRP and BFDP in women with at least four night shifts, an increased risk of breast cancer was associated with variant alleles of SNPs in the genes AANAT (rs3760138, rs4238989), BMAL1 (rs2290035, rs2278749, rs969485) and ROR-b (rs3750420).
- Pubmed
- 23822714
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2013
Drugs