Annotation Detail

Information
Associated Genes
TIMP2
Associated Variants
TIMP2 p.Ser101= (p.S101=) ( ENST00000586057.5, ENST00000586713.6, ENST00000262768.11, ENST00000536189.6, ENST00000585421.5 )
TIMP2 p.Ser101= (p.S101=) ( ENST00000262768.11, ENST00000536189.6, ENST00000585421.5, ENST00000586057.5, ENST00000586713.6 )
Associated Disease
pulmonary emphysema
Source Database
DisGeNET
Description
The TIMP2 rs2277698 SNP was associated with overall (p = 0.022) and paraseptal (p = 0.010) emphysema, as well as with FEV₁/FVC ratio (p = 0.035) and MEF50 (p = 0.008).
Pubmed
23734748
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2013
Drugs