Annotation Detail
Information
- Associated Genes
- PIK3CB
- Associated Variants
-
PIK3CB MUTATION
PIK3CB MUTATION - Associated Disease
- Ki-1+ Anaplastic Large Cell Lymphoma
- Source Database
- DisGeNET
- Description
- In addition to the commonly known AP-1 activators Mitogen-Activated Protein Kinases (MAPKs), there are other signaling pathways, such as PI3K/mTOR/AKT, which are implicated in AP-1 activation/expression in ALCL.
- Pubmed
- 25961698
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs