Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
rs2243250
rs2243250
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
In contrast to a previous study, we found that the -589T polymorphism was associated with a delayed acquisition of X4 HIV-1 variants (RH, 0.56; P = 0.02 for IL-4 -589 C/T or T/T) and a reduced number of CCR5 expressing memory CD4 T cells.
Pubmed
12700447
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.184519152182205
Year of publication
2003
Drugs