Annotation Detail
Information
- Associated Genes
- VEGFA
- Associated Variants
-
VEGFA MUTATION
VEGFA MUTATION - Associated Disease
- Right Ventricular Hypertrophy
- Source Database
- DisGeNET
- Description
- Recently, proangiogenic factors hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) have been known to promote left ventricular myocardial angiogenesis and lead to cardiac hypertrophy, and this would be involved in RV hypertrophy of PH patients.
- Pubmed
- 25301555
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs