Annotation Detail

Information
Associated Genes
ABCG2
Associated Variants
ABCG2 MUTATION
ABCG2 MUTATION
Associated Disease
adrenoleukodystrophy
Source Database
DisGeNET
Description
X-linked Adrenoleukodystrophy (X-ALD), an inherited peroxisomal metabolic neurodegenerative disorder, is caused by mutations/deletions in the ATP-binding cassette transporter (ABCD1) gene encoding peroxisomal ABC transporter adrenoleukodystrophy protein (ALDP).
Pubmed
25393703
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs