Annotation Detail

Information
Associated Genes
ABCG2
Associated Variants
ABCG2 p.Gln141Lys (p.Q141K) ( ENST00000237612.8, ENST00000515655.5, ENST00000650821.1 )
ABCG2 p.Gln141Lys (p.Q141K) ( ENST00000237612.8, ENST00000515655.5, ENST00000650821.1 )
Associated Disease
diarrhea
Source Database
DisGeNET
Description
ABCG2 Q141K polymorphism is associated with chemotherapy-induced diarrhea in patients with diffuse large B-cell lymphoma who received frontline rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone chemotherapy.
Pubmed
19032367
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00609127331760558
Year of publication
2008
Drugs