Annotation Detail

Information
Associated Genes
P2RX7
Associated Variants
P2RX7 p.Gln460Arg (p.Q460R) ( ENST00000328963.10 )
P2RX7 p.Gln460Arg (p.Q460R) ( ENST00000328963.10 )
Associated Disease
bipolar disorder
Source Database
DisGeNET
Description
The P2RX7 (purinergic receptor P2X, ligand-gated ion channel, 7) gene has been suggested as a candidate for major depressive and bipolar disorder, because of repeated associations with the rs2230912 (Gln460Arg) polymorphism.
Pubmed
20446288
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0127254303793718
Year of publication
2010
Drugs