Annotation Detail
Information
- Associated Genes
- IL17RA
- Associated Variants
-
IL17RA p.Lys379= (p.K379=)
(
ENST00000319363.11,
ENST00000612619.2 )
LTA p.Cys13Arg (p.C13R) ( ENST00000454783.5, ENST00000418386.3 )
IL17RA p.Lys379= (p.K379=) ( ENST00000319363.11, ENST00000612619.2 )
LTA p.Cys13Arg (p.C13R) ( ENST00000418386.3, ENST00000454783.5 ) - Associated Disease
- squamous cell carcinoma
- Source Database
- DisGeNET
- Description
- Statistically significant risks were observed for HPV16-containing SCC of the cervix with the variant allele rs879576 in IL17RA and rs2229094 in TNF [OR, 95% CI and multiple-testing corrected p: 1.91 (1.30-2.79), p=0.018 and 0.61 (0.45-0.83), p=0.02, respectively].
- Pubmed
- 26241630
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs