Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET MUTATION
RET MUTATION
Associated Disease
Malignant neoplasm of brain
Source Database
DisGeNET
Description
The majority of the observed loci do not overlap with coding sequences; however, several observed genomic loci overlap with known cancer genes including RET in brain cancers, ERBB2 in renal cell carcinomas, and DCC in ovarian cancers, all of which have not been previously associated with germline changes in cancer.
Pubmed
25644941
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs