Annotation Detail
Information
- Associated Genes
- CXCL8
- Associated Variants
-
CD46 c.674-312G>T
(
ENST00000358170.6,
ENST00000695782.1,
ENST00000360212.6,
ENST00000367047.5,
ENST00000354848.5,
ENST00000367042.6,
ENST00000322875.8,
ENST00000695777.1,
ENST00000367041.5,
ENST00000480003.5,
ENST00000322918.9,
ENST00000695780.1,
ENST00000357714.5 )
NC_000004.12:g.73740307A>T
CXCL8 c.64+230T>G ( ENST00000307407.8, ENST00000401931.1 )
CD46 c.674-312G>T ( ENST00000322875.8, ENST00000322918.9, ENST00000354848.5, ENST00000357714.5, ENST00000358170.6, ENST00000360212.6, ENST00000367041.5, ENST00000367042.6, ENST00000367047.5, ENST00000480003.5, ENST00000695777.1, ENST00000695780.1, ENST00000695782.1 )
NC_000004.12:g.73740307A>T
CXCL8 c.64+230T>G ( ENST00000307407.8, ENST00000401931.1 ) - Associated Disease
- lymphoma
- Source Database
- DisGeNET
- Description
- In line with a previous study, rs2466571 in CD46 (HR = 0.73, 95% CI 0.58-0.91, p = 0.006) showed nominal association with lymphoma progression, as did two highly linked SNPs in IL8 (rs4073 HR = 0.78, 95% CI 0.62-0.97, p = 0.02; rs2227307 HR = 0.75, 95% CI 0.60-0.94, p = 0.01) previously associated with overall survival.
- Pubmed
- 25294155
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00372424133900355
- Year of publication
- 2014
Drugs