Annotation Detail

Information
Associated Genes
TNFAIP3
Associated Variants
TNFSF4 c.-9-15151C>T ( ENST00000714429.1, ENST00000714471.1, ENST00000714430.1, ENST00000714470.1 )
TNFSF4 c.-9-15151C>A ( ENST00000714471.1, ENST00000714470.1, ENST00000714430.1, ENST00000714429.1 )
TNFAIP3 c.296-259C>G ( ENST00000237289.8, ENST00000420009.6, ENST00000421450.2, ENST00000433680.2, ENST00000612899.5 )
rs2736340
TNFSF4 c.-9-15151C>T ( ENST00000714429.1, ENST00000714430.1, ENST00000714470.1, ENST00000714471.1 )
TNFSF4 c.-9-15151C>A ( ENST00000714429.1, ENST00000714430.1, ENST00000714470.1, ENST00000714471.1 )
TNFAIP3 c.296-259C>G ( ENST00000237289.8, ENST00000420009.6, ENST00000421450.2, ENST00000433680.2, ENST00000612899.5 )
rs2736340
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
Single-marker analysis validated the association of BLK rs2736340 (P=4.25×10(-6)) as well as TNFSF4 rs2205960 (P=2.82×10(-5)) and TNFAIP3 rs5029939 (P=1.92×10(-3)) with SLE susceptibility in Chinese.
Pubmed
21905002
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.268175211001211
Year of publication
2012
Drugs