Annotation Detail
Information
- Associated Genes
- MAPK1
- Associated Variants
-
MAPK1 MUTATION
MAPK1 MUTATION - Associated Disease
- Adenocarcinoma of lung (disorder)
- Source Database
- DisGeNET
- Description
- To elucidate how EGFR signaling is linked to metabolic activity, we investigated the involvement of the RAS/MEK/ERK and PI3K/AKT/mammalian target of rapamycin (mTOR) pathways on metabolic alteration in lung adenocarcinoma (LAD) cell lines with activating EGFR mutations.
- Pubmed
- 26023239
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00217153497664243
Drugs