Annotation Detail

Information
Associated Genes
STAT3
Associated Variants
STAT3 MUTATION
STAT3 MUTATION
Associated Disease
Primary Sj�gren's syndrome
Source Database
DisGeNET
Description
IL-22R1 expression on PBMC of pSS was functional, as its stimulation with recombinant IL-22 significantly up-regulated the expression of STAT-3, IL-17 and IL-22.
Pubmed
25880879
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs