Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 MUTATION
ABCA1 MUTATION
Associated Disease
Chronic sinusitis
Source Database
DisGeNET
Description
P-glycoprotein (P-gp) is a membrane-bound efflux pump that is up-regulated in eosinophilic chronic rhinosinusitis and participates in epithelial cytokine secretion.
Pubmed
24717943
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs