Annotation Detail
Information
- Associated Genes
- CA11
- Associated Variants
-
IFNG c.115-456_115-453delCTCG
(
ENST00000229135.4 )
IFNG c.115-456_115-453delCTCG ( ENST00000229135.4 )
rs2069728
rs2069727
IFNG c.367-895T>C ( ENST00000229135.4 )
IFNG c.115-483A>T ( ENST00000229135.4 )
rs2069705
rs2069728
rs2069727
IFNG c.367-895T>C ( ENST00000229135.4 )
IFNG c.115-483A>T ( ENST00000229135.4 )
rs2069705 - Associated Disease
- malaria
- Source Database
- DisGeNET
- Description
- The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).
- Pubmed
- 25445652
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs