Annotation Detail
Information
- Associated Genes
- APOE
- Associated Variants
-
APOE MUTATION
APOE MUTATION - Associated Disease
- Apathy
- Source Database
- DisGeNET
- Description
- Reduced brain-derived neurotrophic factor (BDNF) signaling is considered as a pathogenic event in early Alzheimer's disease (AD), but the influence of apathy and apolipoprotein E ε4 allele (APOE4) on serum BDNF values was not previously investigated in AD.
- Pubmed
- 25024337
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs