Annotation Detail

Information
Associated Genes
GRK4
Associated Variants
GRK4 MUTATION
GRK4 MUTATION
Associated Disease
essential hypertension
Source Database
DisGeNET
Description
In South Africa, GRK4 polymorphisms are more common in people of African descent, associated with impaired Na excretion in normotensive African people, and predict blood pressure response to Na restriction in African patients with mild to moderate essential hypertension.
Pubmed
25775155
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00271441872080303
Drugs