Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
TLR2 MUTATION
TLR2 MUTATION
Associated Disease
Polyendocrinopathies, Autoimmune
Source Database
DisGeNET
Description
These results suggest that immune responses induced by PGA occur via TLR2, TLR6, CD14, and MyD88 through activation of MAP kinase and NF-κB pathways.
Pubmed
26195551
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs