Annotation Detail

Information
Associated Genes
ABCB1
Associated Variants
ABCB1 p.Ser893Ala (p.S893A) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 p.Ser893Thr (p.S893T) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 p.Ser893Ala (p.S893A) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 p.Ser893Thr (p.S893T) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
MDR1 single nucleotide polymorphism G2677T/A and haplotype are correlated with response to docetaxel-cisplatin chemotherapy in patients with non-small-cell lung cancer.
Pubmed
18812689
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.127057488674088
Year of publication
2009
Drugs