Annotation Detail

Information
Associated Genes
STAT3
Associated Variants
STAT3 MUTATION
STAT3 MUTATION
Associated Disease
severe combined immunodeficiency
Source Database
DisGeNET
Description
STAT3 knock-down cells and PL treated cells did not form tumors as well as failed to metastasize in SCID-NSG mice as compared to untreated anchorage-independent cells, which formed big tumors and extensively metastasized.
Pubmed
25216522
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs