Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA c.-94C>G ( ENST00000372067.8, ENST00000425836.9, ENST00000672860.3 )
VEGFA c.-94C>G ( ENST00000372067.8, ENST00000425836.9, ENST00000672860.3 )
Associated Disease
Neurodegenerative Disorders
Source Database
DisGeNET
Description
The aim of the current study is first to demonstrate whether there is an association between the three common VEGF polymorphisms (-2578C/A, -634C/G and 936C/T) in the VEGF gene and idiopathic Parkinson's disease (IPD) which is a neurodegenerative disease caused by the progressive degeneration of nigrostriatal dopaminergic neurons, and second to see if the serum levels of VEGF is reduced in the patients with IPD.
Pubmed
21334418
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00571021083535051
Year of publication
2011
Drugs