Annotation Detail

Information
Associated Genes
PTPRC
Associated Variants
PTPRC MUTATION
PTPRC MUTATION
Associated Disease
B-Cell Lymphomas
Source Database
DisGeNET
Description
The antigenic pattern of bright CD38 and dim CD45 was unique to the MYC-rearranged neoplasms when compared to non-MYC-rearranged aggressive DLBCL (n = 16), with a combined sensitivity of 67% and specificity of 100%, suggesting a shared underlying biology among these MYC rearranged B-cell lymphomas.
Pubmed
24397618
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs