Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
-
TP53 MUTATION
TP53 MUTATION - Associated Disease
- B-Cell Lymphomas
- Source Database
- DisGeNET
- Description
- Mechanistically, 4-MU led to increased p53 mRNA expression, elevated cytoplasmic protein levels of cytochrome c and B-cell lymphoma-2-associated X (BAX) and reduced levels of B-cell lymphoma-2 (BCL2) expression.
- Pubmed
- 26408682
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0392866338847157
Drugs