Annotation Detail

Information
Associated Genes
IL13
Associated Variants
IL13 MUTATION
IL13 MUTATION
Associated Disease
Vascular Diseases
Source Database
DisGeNET
Description
Combined IL-4 and IL-13 deficiency is required for protection against TGF-β-induced pulmonary vascular disease after Schistosoma exposure, and targeted inhibition of this pathway is a potential novel therapeutic approach for patients with schistosomiasis-associated PAH.
Pubmed
26192556
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs