Annotation Detail

Information
Associated Genes
KCNQ1
Associated Variants
KCNQ1 p.Leu266Pro (p.L266P) ( ENST00000713725.1, ENST00000646564.2, ENST00000335475.6, ENST00000155840.12, ENST00000496887.7 )
KCNQ1 p.Leu266Pro (p.L266P) ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000646564.2, ENST00000713725.1 )
Associated Disease
long QT syndrome
Source Database
DisGeNET
Description
Genetic testing in this LQTS population suggests a common KCNQ1 Leu266Pro founder effect, with the descendants clustering in our geographical region even though no common relative has been identified.
Pubmed
19817925
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.41651083741347
Year of publication
2010
Drugs