Annotation Detail

Information
Associated Genes
HHIP
Associated Variants
HYKK c.337+256T>C ( ENST00000569878.5, ENST00000566332.5, ENST00000388988.9 )
ENSG00000285713 c.328-148608G>A
HYKK c.337+256T>C ( ENST00000388988.9, ENST00000566332.5, ENST00000569878.5 )
ENSG00000285713 c.328-148608G>A
Associated Disease
pulmonary emphysema
Source Database
DisGeNET
Description
We found strong genetic associations between the mild upper zone emphysema group and rs1980057 near HHIP, and between the severe emphysema group and rs8034191 in the chromosome 15q region (p<0.001).
Pubmed
24563194
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2014
Drugs