Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
Tuberculosis, Pulmonary
Source Database
DisGeNET
Description
We also performed the analyses by sample types in IL-6 -174 C/G polymorphism, and significant decreased TB risk was observed in pulmonary tuberculosis group (C allele vs. G allele: OR=0.69, 95% CI=0.52-0.93; CG vs. GG: OR=0.69, 95% CI=0.52-0.91; CC+CG vs. GG: OR=0.71, 95% CI=0.55-0.93), and pulmonary tuberculosis plus extra-pulmonary tuberculosis mixed group (CC vs. GG: OR=0.44, 95% CI=0.22-0.88; CC vs. CG+GG: OR=0.48, 95% CI=0.25-0.94).
Pubmed
26169021
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00399568321108385
Drugs