Annotation Detail
Information
- Associated Genes
- TLR4
- Associated Variants
-
TLR4 MUTATION
TLR4 MUTATION - Associated Disease
- Trematode Infections
- Source Database
- DisGeNET
- Description
- In particular, decreased expression of let-7i, a tumor suppressor miRNA, was found to be associated with the ESP-induced upregulation of TLR4 mRNA and protein, which contribute to host immune responses against liver fluke infection.
- Pubmed
- 25217977
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs