Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
rs187084
rs5741883
rs187084
rs5741883
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
A significant difference between TLR9 rs187084 allele frequencies in RA patients and controls was found in one Turkish study (p = 0.003), and a moderate association between RF positivity and TLR8 rs5741883 was found in an European study (p = 0.001).
Pubmed
23325096
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00372424133900355
Year of publication
2013
Drugs