Annotation Detail

Information
Associated Genes
XRCC4
Associated Variants
LIG4 p.Thr9Ile (p.T9I) ( ENST00000687164.1, ENST00000688595.1, ENST00000686204.1, ENST00000688396.1, ENST00000686095.1, ENST00000685338.1, ENST00000686913.1, ENST00000689762.1, ENST00000614526.2, ENST00000611712.4, ENST00000687822.1, ENST00000405925.2, ENST00000693040.1, ENST00000686926.1, ENST00000692222.1, ENST00000688529.1, ENST00000442234.6, ENST00000690127.1, ENST00000688455.1 )
XRCC4 c.894-1G>A ( ENST00000282268.7, ENST00000338635.10, ENST00000396027.9, ENST00000511817.1 )
LIG4 p.Thr9Ile (p.T9I) ( ENST00000405925.2, ENST00000442234.6, ENST00000611712.4, ENST00000614526.2, ENST00000685338.1, ENST00000686095.1, ENST00000686204.1, ENST00000686913.1, ENST00000686926.1, ENST00000687164.1, ENST00000687822.1, ENST00000688396.1, ENST00000688455.1, ENST00000688529.1, ENST00000688595.1, ENST00000689762.1, ENST00000690127.1, ENST00000692222.1, ENST00000693040.1 )
XRCC4 c.894-1G>A ( ENST00000282268.7, ENST00000338635.10, ENST00000396027.9, ENST00000511817.1 )
Associated Disease
Glioma
Source Database
DisGeNET
Description
These results indicate for the first time that LIG4 rs1805388 and XRCC4 rs1805377, alone or in combination, are associated with a risk of gliomas.
Pubmed
23663450
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.007915421552047
Year of publication
2013
Drugs