Annotation Detail

Information
Associated Genes
ATM
Associated Variants
ATM p.Asp1853Asn (p.D1853N) ( ENST00000452508.7, ENST00000278616.10, ENST00000601453.3, ENST00000675843.1, ENST00000713844.1 )
ATM p.Asp1853Asn (p.D1853N) ( ENST00000278616.10, ENST00000452508.7, ENST00000601453.3, ENST00000675843.1, ENST00000713844.1 )
Associated Disease
Brain Neoplasms
Source Database
DisGeNET
Description
The involvement of ATM gene and specifically, the important role of D1853N polymorphism, as a three-hit hypothesis has been previously reported in an Iranian proband affected with brain tumor and this polymorphism could be screened in her relatives as well.
Pubmed
20396981
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00581983144552528
Year of publication
2011
Drugs