Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B MUTATION
IL1B MUTATION
Associated Disease
systemic scleroderma
Source Database
DisGeNET
Description
Immunohistochemical analysis showed stronger staining of NLRP3 and IL-1β cytoplasmic expression in the keratinizing squamous epithelium of skin from SSc patients compared to controls.
Pubmed
25739168
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0188028910002516
Drugs