Annotation Detail

Information
Associated Genes
XPA
Associated Variants
XPA c.-4A>G ( ENST00000375128.5 )
XPA c.-4A>C ( ENST00000375128.5 )
XPA c.-4A>G ( ENST00000375128.5 )
XPA c.-4A>C ( ENST00000375128.5 )
Associated Disease
squamous cell carcinoma
Source Database
DisGeNET
Description
Although smoking is the dominant risk factor of lung cancer, XPA -4G>A (rs1800975) is also associated with the risk of NSCLC, especially for squamous cell carcinoma, among Asian young smokers.
Pubmed
21195504
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0136355639090616
Year of publication
2011
Drugs