Annotation Detail
Information
- Associated Genes
- PTGS2
- Associated Variants
-
NR_125801.1(PACERR):n.536C>G
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
IL13 p.Gln144Arg (p.Q144R) ( ENST00000304506.7 )
NR_125801.1(PACERR):n.536C>G
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL13 p.Gln144Arg (p.Q144R) ( ENST00000304506.7 ) - Associated Disease
- Glioma
- Source Database
- DisGeNET
- Description
- In the single-locus analysis of the 23 examined SNPs, 1 pro-inflammatory and 2 anti-inflammatory gene SNPs were significantly associated with glioma risk (COX2/PTGS2, rs20417 [OR = 1.41]; IL10, rs1800896 [OR = 1.57]; and IL13, rs20541 [OR = 0.39], respectively).
- Pubmed
- 20406895
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.133601888169008
- Year of publication
- 2010
Drugs