Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
SERPINE1 MUTATION
SERPINE1 MUTATION
Associated Disease
pulmonary fibrosis
Source Database
DisGeNET
Description
The biological effects of PAI-1 extend far beyond thrombosis including its critical role in fibrotic disorders, atherosclerosis, renal and pulmonary fibrosis, type-2 diabetes, and cancer.
Pubmed
25386620
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,RGD
DisGENET score for the Gene Disease association
0.0821715349766424
Drugs