Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
IFNG c.115-483A>T
(
ENST00000229135.4 )
CCL17 c.-59-372T>C ( ENST00000219244.9 )
IL19 c.-149+1984T>G ( ENST00000659642.2, ENST00000659997.3, ENST00000656872.2, ENST00000659065.2, ENST00000664374.2 )
IL19 c.-149+2211A>G ( ENST00000664374.2, ENST00000659065.2, ENST00000659642.2, ENST00000659997.3, ENST00000656872.2 )
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
rs1800890 ( ENST00000659997.3, ENST00000656872.2 )
IL1RN p.Ala60= (p.A60=) ( ENST00000259206.9, ENST00000354115.6, ENST00000361779.7, ENST00000409930.4, ENST00000696879.1, ENST00000696881.1 )
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 )
IFNG c.115-483A>T ( ENST00000229135.4 )
CCL17 c.-59-372T>C ( ENST00000219244.9 )
IL19 c.-149+1984T>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2211A>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs1800890 ( ENST00000656872.2, ENST00000659997.3 )
IL1RN p.Ala60= (p.A60=) ( ENST00000259206.9, ENST00000354115.6, ENST00000361779.7, ENST00000409930.4, ENST00000696879.1, ENST00000696881.1 )
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 ) - Associated Disease
- Classical Hodgkin's Lymphoma
- Source Database
- DisGeNET
- Description
- We investigated whether selected germline SNPs in IL10 (rs1800890, rs1800896, rs1800871, rs1800872), TNFA (rs1800629), IL6 (rs1800795), ILRN (rs419598), INFG (rs2430561) and CCL17 (rs223828) were associated with circulating levels of related cytokines at diagnosis and progression-free survival (PFS) in CHL.
- Pubmed
- 24008079
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2013
Drugs