Annotation Detail

Information
Associated Genes
APOA1
Associated Variants
APOA1 MUTATION
APOA1 MUTATION
Associated Disease
psoriasis
Source Database
DisGeNET
Description
In the present study, we demonstrated for the first time that the psoriasis patients with MTHFR-677-T (C/T + T/T) allele had higher serum levels of MDA, VAP-1, APOB and ratio of APOB/APOA1 and dominant/recessive model (CC+CT/TT) and T allele of MTHFR-677 are significantly more common in psoriasis and increased risk of psoriasis by 7.45 and 1.76 fold, respectively.
Pubmed
24118377
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs