Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TNF c.-488G>A
ENSG00000285082 c.-147-423A>G, TLR4 c.94-787A>G ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
TNF c.-488G>A
ENSG00000285082 c.-147-423A>G, TLR4 c.94-787A>G ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
Associated Disease
Allergic rhinitis (disorder)
Source Database
DisGeNET
Description
Children carrying a minor rs1800629 (TNF) or rs1927911 (TLR4) allele may be at a higher risk of allergic rhinitis.
Pubmed
23639307
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00636271518968588
Year of publication
2013
Drugs