Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
LTA c.-9-198A>G
(
ENST00000454783.5,
ENST00000418386.3 )
TNF c.-488G>A
LTA c.-9-198A>G ( ENST00000418386.3, ENST00000454783.5 )
TNF c.-488G>A - Associated Disease
- diffuse large B-cell lymphoma
- Source Database
- DisGeNET
- Description
- Variants in TNFα (rs1800629) (GG vs. AG/AA, p < 0.001) and LTA (rs909253) (AA vs. AG/GG, p = 0.02) and deletions in GSTM1 and GSTT1 (undeleted vs. deleted, p = 0.01 and p = 0.01, respectively) were associated with increased susceptibility of developing DLBCL.
- Pubmed
- 23391141
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00826280829424801
- Year of publication
- 2014
Drugs