Annotation Detail
Information
- Associated Genes
- APOE
- Associated Variants
-
APOE MUTATION
APOE MUTATION - Associated Disease
- pseudoxanthoma elasticum
- Source Database
- DisGeNET
- Description
- Increased cholesterol biosynthesis, elevated PCSK9 levels and reduced APOE mRNA expression newly found in PXE fibroblasts could enforce atherogenesis and cardiovascular risk in PXE patients.
- Pubmed
- 25064003
- Section of the abstract supporting the evidence
- CONCLUSION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs