Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF c.-488G>A
TNF c.-488G>A
Associated Disease
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
Source Database
DisGeNET
Description
TNF rs1800629 was associated with risk of NHL (OR 1.53, 95% confidence interval, CI, 1.06-2.19 for minor allele homozygosity), T-cell lymphoma (OR 2.54, CI 1.27-5.09) and mantle cell lymphoma (OR 2.84, CI 1.38-5.87).
Pubmed
20087644
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2010
Drugs