Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
LTA c.-9-198A>G
(
ENST00000454783.5,
ENST00000418386.3 )
TNF c.-488G>A
LTA c.-9-198A>G ( ENST00000418386.3, ENST00000454783.5 )
TNF c.-488G>A - Associated Disease
- Lymphoma, Non-Hodgkin
- Source Database
- DisGeNET
- Description
- Two single nucleotide polymorphisms (SNPs) in adjacent genes, lymphotoxin alpha (LTA +252G, rs909253 A>G) and tumor necrosis factor (TNF -308A, rs1800629 G>A), form the G-A haplotype repeatedly associated with increased risk of non-Hodgkin lymphoma (NHL) in individuals uninfected with HIV-1.
- Pubmed
- 19654554
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0497499406807093
- Year of publication
- 2009
Drugs