Annotation Detail

Information
Associated Genes
IL10
Associated Variants
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
rs266729
ADIPOQ p.Gly15= (p.G15=) ( ENST00000320741.7, ENST00000444204.2 )
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 )
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs266729
ADIPOQ p.Gly15= (p.G15=) ( ENST00000320741.7, ENST00000444204.2 )
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 )
Associated Disease
gestational diabetes
Source Database
DisGeNET
Description
Our study aimed to assess in vitro production of IL-10, IL-6, TNF-A, and adiponectin serum levels in pregnant women with and without gestational diabetes mellitus (GDM) and to investigate a possible association between GDM and IL-10-1082 A>G (rs1800896), IL-6-174 G>C (rs1800795), TNF-A-308 G>A (rs1800629), adiponectin +45 T>G (rs2241766), and adiponectin-11377 C>G (rs266729) gene polymorphisms.
Pubmed
22070425
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00290991572276264
Year of publication
2012
Drugs